Nor, they said, do they believe such prescribing is happening to any significant extent. Statisticians in analyzed real world data, hundreds of thousands of medical insurance claims involving people with rheumatoid arthritis and other inflammatory diseases, according to the Pfizer PowerPoint obtained by The Post. Then they checked for Enbrel treatment.
The numbers may seem small, but they were mirrored in the same proportion when the researchers checked insurance claims information from another database.
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The Pfizer team also produced closely similar numbers for Humira, a drug marketed by AbbVie that works like Enbrel. A clinical trial to prove the hypothesis would take four years and involve 3, to 4, patients, according to the Pfizer document that recommended a trial. Enbrel reduces inflammation by targeting a specific protein called TNF-a. Still, a long-term follow-up of one of those trials indicated a benefit if NSAID use began when the brain was still normal, suggesting the timing of therapy could be key.
Pfizer said it also was skeptical because Enbrel has only a limited effect on the brain. It is a fair hypothesis that fighting inflammation outside the brain with Enbrel will have a similar effect inside the brain, he said. New claim made in Trump inquiry. Protests in Bolivia over interim head. Lopez considered quitting showbiz.
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